Chromosomal Theory of Inheritance
Mitosis:
 
 
Meiosis:
 
 
Problems:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
X-Linked Inheritance:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
FlyLab:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Tutorial
Animation and description of phases of mitosis
 
Tutorial
Animation and description of phases of meiosis
 
1. Mitosis
Stages of cell cycle
"c" vs "n"
DNA replication, sister chromatids, homologous chromosomes
Mitotic division phases
Alleles on sister chromatids
Drag and drop chromosomes to emulate mitosis
 
2. Meiosis
Consequences of sexual reproduction without meiosis
Drag and Drop chromosomes to emulate meiosis I
Drag and Drop chromosomes to emulate meiosis II
Number of gametes formed
Phases of meiosis, values of c, n
Karyotypes
Sex chromosomes
 
3. Independent Assortment
Drag and Drop two pairs of chromosomes to emulate meiosis I
Gametes formed during meiosis II
Linkage: independent assortment of chromosomes not necessarily markers
 
4. Microscopy
Mitosis vs meiosis
"c" vs "n"
haploid vs diploid
 
Problems
 
1. X linked recessive trait
Dominant vs recessive
X linked vs autosomal
Genotypes
 
2. X linked recessive trait (Hemophilia)
Genotypes
Probability of affected children
 
3. X linked dominant trait (Vitamin D rickets)
Dominant vs recessive
X linked vs autosomal
Genotypes
Probabilities
 
4. X linked common recessive trait (Red green colorblindness) and Sickle cell anemia (autosomal recessive)
Independent Assortment
Probabilities
 
5. Nondisjunction
Colorblindness and Turner syndrome
Colorblindness and Klinefelter syndrome
Identify parent where nondisjunction occurred
Nondisjunction in Meiosis I or II
White eyes in flies
Sex determination in flies
 
1. Monhybrid cross, recessive (brown)
Dominant vs recessive
Drosophila nomenclature
Genotypes
Testcross
Phenotypic ratios
 
2. Monohybrid cross, dominant (lobed)
Dominant vs recessive
Drosophila nomenclature
Genotypes
 
3. Monohybrid cross, X linked recessive (white)
Reciprocal crosses to F2
Dominant vs recessive
X linked vs autosomal
Drosophila nomenclature
Genotypes
Phenotypic ratios
 
4. Monohybrid cross, X linked dominant (Bar)
Reciprocal crosses to F2
Dominant vs recessive
X linked vs autosomal
Drosophila nomenclature
Genotypes
Phenotypic ratios
 
5. Dihybrid cross, two autosomal recessives (ebony, purple)
Dominant vs recessive
X linked vs autosomal
Genotypes
Phenotypic ratios
Testcross
Testcross ratios
 
6. Dihybrid cross, X linked and autosomal (sable, dumpy)
Reciprocal crosses
Dominant vs recessive
X linked vs autosomal
Genotypes
Phenotypic ratios
Testcross
Testcross ratios